Great Depression
- Roel, José García
- Rolla, Lenora Butler
- Ross, Helene Elaine Cole
- Rountree, Frances Mitchell
- Ruiz, John Joseph
- Rural Electrification
- Ryan, James Delbridge
- Sabin, Lorenzo Sherwood, Jr.
- Sabine Farms, Texas
- Sáenz, José de la Luz
- Sager, Manuela Solís
- Sakowitz, Bernard
- Sakowitz, Simon
- Sakowitz, Tobias
- Salas Aldaz, Fernando
- San Antonio Citizens League
- San Antonio Conservation Society
- San Antonio, TX
- San Jacinto Centennial Association
- San Jacinto Monument and Museum
- San Jacinto River Authority
- Saunders, Edna Dee Woolford
- Schwartz, Sam
- Scott, Bess Whitehead
- Segregation
- Sellers, James Earl [J. E., Pop]
- Selph, Leon [Pappy]
- Sheehan, Mary Louise [Sister Mary Agatha]
- Sheppard, John Morris
- Sherman Riot of 1930
- Simmons, David Andrew
- Simon, Jewel Alma Woodard
- Simpson, Lee Haywood
- Sisters of Charity of the Incarnate Word, Houston
- Smith, Antonio Maceo
- Smith, Ernest Ollington
- Smith, Frank Chesley
- Smith, Hilton Lee
- Smith, Lonnie E.
- Smith, Robert Everett
- Sons of the Republic of Texas
- South Texas College of Law
- Spivey, Victoria Regina
- Spring Valley, TX (Harris County)
- St. George Orthodox Christian Church
- St. Mary's Seminary
- St. Thomas High School
- Stanton, George Elliott
- Star Bottling Works
- Starks, Maggie Fulleylove